No Mo Whining or I3C is useful to restore a healthier progesterone to estrogen ratio in women by reducing the ratio of estradiol (unhealthy estrogen) relative to estrodiol and estriol and progesterone menopausal symptoms are relieved without the use of progestins. It also helps restore healthy testosterone to estrogen ratios in men.

The result is increased skin moisture, vaginal lubrication and improved libido.

Further, I3C is thought to be cancer-protective (probably through the reduction of estradiol levels.)

I3C (Indole-3-carbinol) inhibits degradation of testosterone into estradiol (E-2). Additionally this favors production of 2-hydroxy estrone and decreases the production of 16-hydroxy and 4-hydroxy estrone. Increases in 16-hydroxy estrone levels may be associated with breast neoplasm and 2-hydroxyestrone may be cytoprotective. 

No Mo Whining features indole-3-carbinol (I3C) which promotes healthy estrogen metabolism and estrogenic activity. I3C is a naturally occurring compound found in cruciferous vegetables such as broccoli brussels sprouts and cabbage.

• Supports the health of estrogen-sensitive tissues by promoting the formation of the beneficial estrogen metabolite 2-hydroxyestrone. 
  
• Supports the detoxification of estrogens other steroid hormones and xenoestrogens by enhancing the activity of enzymes involved in their metabolism and excretion. 
  
• May be especially beneficial for women with estrogen-related health concerns. Beneficial to men by reducing testosterone transformation into estrogen.
  
• Specially combined with rosemary extract to reduce oxidation and packaged with a desiccant to reduce moisture-measures that help to ensure potency.